Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079929 | 0.81 | CHRM1 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5052648 | 0.73 | HSP90B1 (0.47) | HSP90B1HDAC1HDAC6CHRM1AHR | |
| SCHEMBL1953325 | 0.71 | ATR (0.46) | KDM4EPOLBALDH1A1GLAGAA | |
| SCHEMBL1607759 | 0.70 | HDAC6 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28525168 | 0.70 | FGFR1 (0.40) | KDM4EALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL699995 | 0.70 | APP (0.50) | POLBL3MBTL1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL21043082 | 0.70 | L3MBTL1 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3802315 | 0.70 | HSP90AA1 (0.51) | HDAC4HDAC1HDAC2HDAC6CHRM1 | |
| SCHEMBL27988410 | 0.69 | LMNA (0.40) | KDM4EL3MBTL1ASPHKDM8ALDH1A1 | |
| SCHEMBL21518857 | 0.69 | SMN1; SMN2 (0.45) | HDAC1KDM4EL3MBTL1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390799-B | Nitrogen-containing heterocyclic 5-HT3 receptor regulator and preparation method and application thereof | 科岭源生物科技(深圳)有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-112390799-A | Nitrogen-containing heterocyclic 5-HT3 receptor regulator and preparation method and application thereof | 成都科岭源医药技术有限公司 | 2021-02-23 | — | — | CN | disclosed |