Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524703 | 0.87 | IDO1 (0.58) | IDO1DAOFFAR1PDE2AAGXT | |
| SCHEMBL12516416 | 0.77 | IDO1 (0.67) | IDO1DAOFFAR1PDE2AAGXT | |
| SCHEMBL16214946 | 0.77 | IDO1 (0.67) | IDO1DAOFFAR1PDE2AAGXT | |
| SCHEMBL3156002 | 0.75 | IDO1 (0.63) | IDO1DAOFFAR1PDE2AAGXT | |
| SCHEMBL6789942 | 0.74 | IDO1 (0.58) | IDO1DAOFFAR1PDE2ASLC6A4 | |
| SCHEMBL1117948 | 0.74 | IDO1 (0.58) | IDO1DAOFFAR1PDE2ASLC6A4 | |
| SCHEMBL7977134 | 0.74 | IDO1 (0.62) | IDO1DAOFFAR1PDE2ASLC6A4 | |
| SCHEMBL27634838 | 0.74 | IDO1 (0.58) | IDO1DAOFFAR1PDE2ASLC6A4 | |
| SCHEMBL19409499 | 0.74 | IDO1 (0.58) | IDO1DAOFFAR1PDE2ASLC6A4 | |
| SCHEMBL14255637 | 0.74 | IDO1 (0.58) | IDO1DAOFFAR1PDE2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364684-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-112867720-A | Novel heterocyclic compounds as monoacylglycerol lipase inhibitors | 豪夫迈·罗氏有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-112469724-A | Novel heterocyclic compounds as monoacylglycerol lipase inhibitors | 豪夫迈·罗氏有限公司 | 2021-03-09 | — | — | CN | disclosed |