Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31638152 | 0.88 | HTR7 (0.48) | HTR7KMT2ADDB1CRBNKDM4E | |
| SCHEMBL31637930 | 0.86 | HTR7 (0.51) | HTR7KMT2AKDM4EALDH1A1MAPK8 | |
| SCHEMBL8892987 | 0.83 | HTR7 (0.50) | HTR7KDM4EALDH1A1SMN1; SMN2MAPK8 | |
| SCHEMBL31748070 | 0.81 | KDM4E (0.44) | DDB1CRBNKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13141152 | 0.81 | DDB1 (0.37) | KMT2ADDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL20592493 | 0.81 | KDM4E (0.44) | DDB1CRBNKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22396731 | 0.80 | PSEN1 (0.42) | DDB1CRBNKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3804347 | 0.78 | KMT2A (0.50) | HTR7KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3164076 | 0.78 | POLB (0.36) | KMT2ADDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL1291191 | 0.77 | TSHR (0.56) | DDB1CRBNKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423758-A | Adenosine receptor binding compounds | 尼康治疗公司 | 2021-02-26 | — | — | CN | disclosed |