Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.62 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.62 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198016 | 0.83 | TRIM24 (0.65) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL7192327 | 0.81 | CYP1A2 (0.63) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| SCHEMBL4267088 | 0.80 | ERN1 (0.43) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL3604055 | 0.80 | TRIM24 (0.43) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL26675937 | 0.80 | ALDH1A1 (0.50) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL9358828 | 0.80 | TRIM24 (0.60) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL3210928 | 0.79 | TRIM24 (0.69) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL16421968 | 0.78 | ERN1 (0.44) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL4914344 | 0.77 | TRIM24 (0.62) | TYRTRIM24TRIM33CYP1A1CYP1A2 | |
| SCHEMBL16475652 | 0.77 | TRIM24 (0.67) | TYRTRIM24TRIM33CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300042-B | 4-benzo five-membered ring-phenyl sulfonium salt compound and preparation method and application thereof | 同济大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-112300042-A | 4-benzo five-membered ring-phenyl sulfonium salt compound and preparation method and application thereof | 同济大学 | 2021-02-02 | — | — | CN | disclosed |