Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643810 | 0.83 | HTT (0.54) | ALDH1A1HIF1AHTTHSPB1S1PR4 | |
| SCHEMBL3032438 | 0.80 | XDH (0.52) | ALDH1A1HSPB1MAPTLMNA | |
| SCHEMBL5866590 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTS1PR4MAPT | |
| SCHEMBL20335461 | 0.80 | HTT (0.49) | ALDH1A1HIF1ASMN1; SMN2HTTHSPB1 | |
| SCHEMBL16848696 | 0.80 | CYP19A1 (0.61) | ALDH1A1HIF1ASMN1; SMN2HTTHSPB1 | |
| SCHEMBL31506375 | 0.80 | CYP19A1 (0.57) | ALDH1A1HIF1ASMN1; SMN2HTTHSPB1 | |
| SCHEMBL25797159 | 0.80 | CYP19A1 (0.57) | ALDH1A1HIF1ASMN1; SMN2HTTHSPB1 | |
| SCHEMBL2144346 | 0.79 | S1PR4 (0.52) | ALDH1A1HIF1ASMN1; SMN2HTTHSPB1 | |
| SCHEMBL29400372 | 0.79 | S1PR4 (0.52) | ALDH1A1HIF1ASMN1; SMN2HTTHSPB1 | |
| SCHEMBL3167961 | 0.79 | MAPT (0.60) | ALDH1A1SMN1; SMN2MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836819-A | Arylamine-substituted pyrrolopyrimidine compound, and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |