Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176880 | 0.84 | LMNA (0.53) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL3979969 | 0.84 | LMNA (0.53) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30535283 | 0.84 | LMNA (0.82) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL676142 | 0.84 | LMNA (0.82) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| Potassium SCHEMBL6776357 | 0.81 | LMNA (0.78) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14820292 | 0.80 | LMNA (0.49) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL16114401 | 0.79 | LMNA (0.75) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11610555 | 0.78 | LMNA (0.55) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL29782927 | 0.78 | LMNA (0.55) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL22061921 | 0.77 | LMNA (0.87) | LMNATDP1CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384507-A | Substituted 4-heteroaryloxypyridines and their salts and their use as herbicides | 拜耳公司 | 2021-02-19 | — | — | CN | disclosed |