Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.64 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30535283 | 1.00 | LMNA (0.82) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| Potassium SCHEMBL6776357 | 0.97 | LMNA (0.78) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16114401 | 0.95 | LMNA (0.75) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL78141 | 0.93 | LMNA (0.72) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29500180 | 0.93 | LMNA (0.72) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL22061921 | 0.93 | LMNA (0.87) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| Bromide SCHEMBL9391382 | 0.91 | LMNA (0.69) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27968872 | 0.91 | LMNA (0.69) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9386460 | 0.91 | LMNA (0.69) | LMNATDP1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11107948 | 0.85 | LMNA (0.62) | LMNATDP1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303150-A | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2020-06-19 | — | — | CN | claimed |
| US-20090253728-A1 | Methods and Compositions for Treating Nociceptive Pain | MEYERSON LAURENCE R | 2009-10-08 | — | — | US | claimed |
| EP-1789028-A2 | COMPOSITIONS FOR TREATING NOCICEPTIVE PAIN | Neuromolecular Pharmaceuticals Inc (US) | 2007-05-30 | — | — | EP | claimed |
| US-20060052370-A1 | Methods and compositions for treating nociceptive pain | NEUROMOLECULAR, INC. | 2006-03-09 | — | — | US | claimed |
| WO-2006024018-A2 | COMPOSITIONS FOR TREATING NOCICEPTIVE PAIN | NEUROMOLECULAR PHARMACEUTICALS, INC. (US) | 2006-03-02 | — | — | WO | claimed |
| US-4874775-A | INHIBIT PHYTOPATHOGENS | ELI LILLY AND COMPANY (US) | 1989-10-17 | — | — | US | claimed |
| EP-3200801-B1 | METHODS OF TREATING PANCREATIC CANCER | UNIV MARYLAND (US) | 2024-04-24 | — | — | EP | disclosed |
| US-11707468-B2 | Methods of treating pancreatic cancer | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-07-25 | — | — | US | disclosed |
| EP-3921324-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | Memorial Sloan Kettering Cancer Center (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2021107590-A1 | NOVEL TRIAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 대웅제약 | 2021-06-03 | — | — | WO | disclosed |
| US-20200261475-A1 | METHODS OF TREATING PANCREATIC CANCER | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-08-20 | — | — | US | disclosed |
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |
| US-10675289-B2 | Methods of treating pancreatic cancer | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-06-09 | — | — | US | disclosed |
| US-4874775-A | INHIBIT PHYTOPATHOGENS | ELI LILLY AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| US-4698091-A | 2-phenylpyrimidines, 2-naphthylpyrimidines and 2-heterocyclylpyrimidines as safeners for protecting cultivated plant against phytotoxic damage caused by herbicides | CIBA-GEIGY CORPORATION (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0206581-A2 | Agriculturally-useful sulfonamides | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| CN-86103621-A | The method of the sulphonamide of preparation agriculturally useful | — | 1986-12-10 | — | — | CN | disclosed |
| EP-0148826-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000289-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH COMPANY (US) | 1985-01-31 | — | — | WO | disclosed |
| US-4407806-A | PRE- AND POSTEMERGENCE HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10675289-B2 | Methods of treating pancreatic cancer | RNASE1, PNLIP, AMY2A | LMNA 2274/4885TDP1 3214/4885CYP19A1 3488/4885 |
| US-11707468-B2 | Methods of treating pancreatic cancer | RNASE1, PNLIP, AMY2A | LMNA 2274/4885TDP1 3214/4885CYP19A1 3488/4885 |
| US-20200261475-A1 | METHODS OF TREATING PANCREATIC CANCER | RNASE1, PNLIP, AMY2A | LMNA 2274/4885TDP1 3214/4885CYP19A1 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.