SCHEMBL28525620

SCHEMBL28525620

CCCCC(CC)COC(=O)CCC(C)c1cc(-c2c(Cl)ccc3[nH]nnc23)c(O)c(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
MAPK1 P28482 2/20 0.37
CYP3A4 P08684 2/20 0.36
TSHR P16473 2/20 0.36
ATM Q13315 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 1/20 0.32
CA2 P00918 1/20 0.32
GAA P10253 1/20 0.30
XBP1 P17861 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760490 0.88 ALDH1A1 (0.38) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL29565164 0.80 ALDH1A1 (0.39) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL27328187 0.79 CYP3A4 (0.39) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL4887850 0.75 CYP3A4 (0.39) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL3188077 0.74 GAA (0.36) ALDH1A1GAA
SCHEMBL5329783 0.70 GAA (0.40) ALDH1A1LMNAGAA
SCHEMBL990405 0.69 ALDH1A1 (0.42) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL27363585 0.69 CYP3A4 (0.31) ALDH1A1CYP3A4LMNACA2
SCHEMBL29470088 0.68 HSP90AA1 (0.41) CYP3A4TSHR
SCHEMBL29733675 0.68 HSP90AA1 (0.41) CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112292382-A 3-phenylbenzofuran-2-one diphosphate derivatives as stabilizers 巴斯夫欧洲公司 2021-01-29 CN disclosed