SCHEMBL7760490

SCHEMBL7760490

CCCCC(CC)COC(=O)CCc1cc(-c2c(Cl)ccc3[nH]nnc23)c(O)c(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPK1 P28482 2/20 0.38
CYP3A4 P08684 3/20 0.37
TSHR P16473 2/20 0.37
ATM Q13315 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
GAA P10253 2/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 2/20 0.33
CA2 P00918 1/20 0.32
XBP1 P17861 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HSD17B10 Q99714 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29565164 0.90 ALDH1A1 (0.39) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL28525620 0.88 ALDH1A1 (0.37) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL4887850 0.87 CYP3A4 (0.39) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL3188077 0.87 GAA (0.36) ALDH1A1GAAKMT2AGSK3B
SCHEMBL27328187 0.83 CYP3A4 (0.39) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL5329783 0.83 GAA (0.40) ALDH1A1GAAKMT2ALMNAGSK3B
SCHEMBL990405 0.80 ALDH1A1 (0.42) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL17627924 0.80 ALDH1A1 (0.46) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL284444 0.79 CYP3A4 (0.56) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL3005960 0.79 CYP3A4 (0.40) ALDH1A1MAPK1CYP3A4TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461396-B Additive composition and use thereof, condensation polymer composition, molding compound prepared from same and molded part and use thereof 弗劳恩霍夫应用研究促进协会 2024-07-12 CN disclosed
CN-118234793-A Stabilizer based on syringic acid, vanillic acid, isovanillic acid or 5-hydroxyveratric acid, plastic composition, method for stabilizing a plastic composition and stabilizer composition 弗劳恩霍夫应用研究促进协会 2024-06-21 CN disclosed
CN-114555695-B Thermoplastic resin composition and molded article comprising same 株式会社LG化学 2024-04-19 CN disclosed
CN-113348205-B Method for stabilizing halogen-free thermoplastic recyclates, plastic compositions, stabilizer compositions and use of stabilizer compositions 弗劳恩霍夫应用研究促进协会 2024-02-27 CN disclosed
CN-109790465-B Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2024-01-02 CN disclosed
CN-111448250-B Method for stabilizing halogen-free thermoplastic recycling materials, stabilized plastic compositions and molding compounds and molded parts produced therefrom 弗劳恩霍夫应用研究促进协会 2023-07-14 CN disclosed
CN-114555698-B Thermoplastic resin composition and molded article thereof 株式会社LG化学 2023-07-04 CN disclosed
CN-116348552-A Thermoplastic resin and molded article produced using the same 株式会社LG化学 2023-06-27 CN disclosed
CN-110678510-B Nucleating agents, methods of making the same and related polymer compositions 巴斯夫欧洲公司 2022-03-29 CN disclosed
CN-113597416-A Shaped synthetic polymer article 巴斯夫欧洲公司 2021-11-02 CN disclosed
CN-112639034-A UV curable composition for 3D printing 巴斯夫欧洲公司 2021-04-09 CN disclosed
CN-111902477-A Use of ultraviolet radiation absorbing polymer composition (UVRAP) as UV absorber in coatings for non-biological and non-keratin materials 巴斯夫欧洲公司 2020-11-06 CN disclosed
EP-1087947-A2 TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CONTAINING HINDERED PHENOLS Ciba SC Holding AG (CH) 2001-04-04 EP disclosed
WO-1999067223-A2 TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CONTAINING HINDERED PHENOLS CYTEC TECH CORP (US) 1999-12-29 WO disclosed
CN-1132763-A Low-dust granules of plastic additives CIBA GEIGY AG (CH) 1996-10-09 CN disclosed
US-4880859-A GROUP TRANSFER POLYMERIZATION, COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 US disclosed