Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855842 | 0.86 | ALDH1A1 (0.55) | TDP1L3MBTL1EPHX2CYP1A2CYP2C9 | |
| SCHEMBL6160971 | 0.81 | EPHX2 (0.55) | POLBEPHX2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5804037 | 0.81 | CYP1A2 (0.59) | L3MBTL1EPHX2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5914903 | 0.80 | DHODH (0.57) | TDP1POLBL3MBTL1EPHX2CYP1A2 | |
| SCHEMBL5914904 | 0.80 | DHODH (0.57) | TDP1POLBL3MBTL1EPHX2CYP1A2 | |
| SCHEMBL2347463 | 0.78 | EPHX2 (0.49) | EPHX2CYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL28526011 | 0.77 | EPHX2 (0.48) | POLBEPHX2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7778855 | 0.77 | EPHX2 (0.65) | TDP1POLBL3MBTL1EPHX2RXFP1 | |
| SCHEMBL201743 | 0.76 | EPHX1 (0.63) | TDP1POLBL3MBTL1RXFP1 | |
| SCHEMBL8155266 | 0.75 | EPHX2 (0.41) | L3MBTL1EPHX2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112472699-A | Combination methods for improving the therapeutic benefit of bisantrene and derivatives | 种族肿瘤学公司 | 2021-03-12 | — | — | CN | disclosed |