Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193206 | 0.89 | LMNA (0.41) | LMNASMN1; SMN2THRBHIF1ATDP1 | |
| SCHEMBL7210264 | 0.89 | LMNA (0.41) | LMNASMN1; SMN2THRBHIF1ATDP1 | |
| SCHEMBL8192203 | 0.87 | LMNA (0.41) | LMNASMN1; SMN2THRBHIF1ATDP1 | |
| SCHEMBL284985 | 0.86 | LMNA (0.69) | LMNAMGLLSMN1; SMN2MAPTNT5E | |
| SCHEMBL284984 | 0.86 | LMNA (0.69) | LMNAMGLLSMN1; SMN2MAPTNT5E | |
| SCHEMBL8192660 | 0.85 | LMNA (0.42) | LMNASMN1; SMN2THRBHIF1ATDP1 | |
| SCHEMBL7209690 | 0.85 | LMNA (0.42) | LMNASMN1; SMN2THRBHIF1ATDP1 | |
| SCHEMBL285510 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2THRBHIF1ATDP1 | |
| SCHEMBL9413897 | 0.85 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL9057265 | 0.84 | LMNA (0.54) | LMNASMN1; SMN2THRBHIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | claimed |
| EP-0602454-B1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | HOFFMANN LA ROCHE (CH) | 1996-04-24 | — | — | EP | claimed |
| EP-0602454-A1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | claimed |
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| EP-0602454-B1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | HOFFMANN LA ROCHE (CH) | 1996-04-24 | — | — | EP | disclosed |
| EP-0602454-A1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |