Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193206 | 1.00 | LMNA (0.41) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| SCHEMBL8192203 | 0.98 | LMNA (0.41) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| SCHEMBL7209690 | 0.96 | LMNA (0.42) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| SCHEMBL8192660 | 0.96 | LMNA (0.42) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| SCHEMBL285261 | 0.89 | LMNA (0.51) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| SCHEMBL3817265 | 0.87 | LMNA (0.46) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| SCHEMBL3817191 | 0.86 | LMNA (0.51) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| SCHEMBL8184925 | 0.86 | LMNA (0.55) | LMNAADK | |
| SCHEMBL7208745 | 0.86 | LMNA (0.55) | LMNAADK | |
| SCHEMBL7211564 | 0.86 | LMNA (0.37) | LMNASMN1; SMN2ALDH1A1ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |