Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298369 | 0.96 | TDP1 (0.45) | ALDH1A1TDP1ATMMAPTPKM | |
| SCHEMBL20703549 | 0.90 | TDP1 (0.42) | ALDH1A1TDP1ATMMAPTSMN1; SMN2 | |
| SCHEMBL20703719 | 0.88 | MAPT (0.41) | ALDH1A1TDP1ATMMAPTSMN1; SMN2 | |
| SCHEMBL3714546 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TDP1ATMMAPTPKM | |
| SCHEMBL9606830 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MAPTPKMSMN1; SMN2MAPK1 | |
| SCHEMBL25947445 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5676255 | 0.84 | TDP1 (0.44) | ALDH1A1TDP1ATMMAPTSMN1; SMN2 | |
| SCHEMBL3223924 | 0.84 | TDP1 (0.44) | ALDH1A1TDP1ATMMAPTPKM | |
| SCHEMBL1201863 | 0.83 | AKR1C3 (0.46) | ALDH1A1TDP1ATMMAPTSMN1; SMN2 | |
| SCHEMBL3726022 | 0.82 | TSHR (0.49) | ALDH1A1TDP1MAPTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | disclosed |