SCHEMBL9606830

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2298369	0.89	TDP1 (0.45)	ALDH1A1KMT2ALMNAMAPTMEN1
	SCHEMBL12710192	0.89	L3MBTL1 (0.46)	ALDH1A1KMT2ALMNAHTTMAPT
	SCHEMBL13594699	0.86	GRM8 (0.43)	ALDH1A1KMT2ALMNAHTTMAPT
	SCHEMBL28526142	0.86	ALDH1A1 (0.47)	ALDH1A1KMT2ALMNAMAPTNPC1
	SCHEMBL20703549	0.86	TDP1 (0.42)	ALDH1A1KMT2AMAPTMEN1MAPK1
	SCHEMBL3722430	0.84	ALDH1A1 (0.44)	ALDH1A1KMT2ALMNAHTTMAPT
	SCHEMBL2435441	0.83	MYC (0.48)	ALDH1A1KMT2ALMNAHTTMAPT
	SCHEMBL13014980	0.83	AKR1C3 (0.42)	ALDH1A1KMT2ALMNAHTTMEN1
	SCHEMBL20703719	0.82	MAPT (0.41)	ALDH1A1KMT2ALMNAMAPTMEN1
	SCHEMBL287712	0.81	KDM4E (0.43)	ALDH1A1LMNAHTTMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.