SCHEMBL28526153

SCHEMBL28526153

NC1(c2cc(C3(N)C=CC(c4ccccc4)=CC3)cc(C3(N)C=CC(c4ccccc4)=CC3)c2)C=CC(c2ccccc2)=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28396976 0.91 PNMT (0.34)
SCHEMBL27568341 0.89 ADORA2A (0.31)
SCHEMBL25383769 0.85 HSD17B10 (0.39)
SCHEMBL5852516 0.82 HSD17B10 (0.46)
SCHEMBL714828 0.81 CYP3A4 (0.39)
SCHEMBL29144705 0.81 NOTUM (0.30)
Hydrochloric Acid SCHEMBL8638713 0.80 CYP3A4 (0.38)
SCHEMBL8953979 0.80 HSD17B10 (0.42)
SCHEMBL31326885 0.80 ALDH1A1 (0.34)
SCHEMBL31326887 0.79 CYP3A4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118002203-A Preparation method and application of spinel-covalent organic framework composite material 河北工业大学 2024-05-10 CN claimed
CN-115466186-B Light response simulated oxidase based on highly conjugated COFs and preparation method and application thereof 四川大学 2023-10-10 CN claimed
CN-115466186-A Photoresponse simulated oxidase based on highly conjugated COFs (conjugated COFs), and preparation method and application thereof 四川大学 2022-12-13 CN claimed
CN-108794743-B Preparation method of large-aperture organic covalent framework material 盐城师范学院 2021-02-19 CN claimed
US-12447437-B2 Carbon dioxide adsorption-desorption device KABUSHIKI KAISHA TOSHIBA (JP) 2025-10-21 US disclosed
CN-119654742-A Separator, secondary battery, and electricity device 宁德时代新能源科技股份有限公司 2025-03-18 CN disclosed
CN-119522508-A Separator, secondary battery, and electricity using device 宁德时代新能源科技股份有限公司 2025-02-25 CN disclosed
CN-115894947-B Two-dimensional covalent organic framework material with micropore and kgd topological network structure and preparation and application thereof 浙江工业大学 2023-10-20 CN disclosed
CN-115466186-B Light response simulated oxidase based on highly conjugated COFs and preparation method and application thereof 四川大学 2023-10-10 CN disclosed
CN-115466186-B Light response simulated oxidase based on highly conjugated COFs and preparation method and application thereof 四川大学 2023-10-10 CN disclosed
CN-115894947-A Two-dimensional covalent organic framework material with micropore and kgd topological network structure and preparation and application thereof 浙江工业大学 2023-04-04 CN disclosed
US-20230102938-A1 CARBON DIOXIDE ADSORPTION-DESORPTION DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2023-03-30 US disclosed
CN-115466186-A Photoresponse simulated oxidase based on highly conjugated COFs (conjugated COFs), and preparation method and application thereof 四川大学 2022-12-13 CN disclosed
CN-115466186-A Photoresponse simulated oxidase based on highly conjugated COFs (conjugated COFs), and preparation method and application thereof 四川大学 2022-12-13 CN disclosed
CN-114214751-A Covalent bond organic framework nanofiber and preparation method and application thereof 南方科技大学 2022-03-22 CN disclosed
CN-108794743-B Preparation method of large-aperture organic covalent framework material 盐城师范学院 2021-02-19 CN disclosed
CN-108794743-B Preparation method of large-aperture organic covalent framework material 盐城师范学院 2021-02-19 CN disclosed