Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533797 | 1.00 | MEN1 (0.40) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL28527483 | 0.91 | MPO (0.38) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL28540055 | 0.87 | HCRTR2 (0.47) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL28909603 | 0.87 | HCRTR2 (0.47) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL20170480 | 0.87 | HCRTR2 (0.47) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL28526506 | 0.83 | TAAR1 (0.42) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL17345636 | 0.82 | MPO (0.48) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL28236055 | 0.81 | ADRA2B (0.36) | — | |
| SCHEMBL28532896 | 0.81 | SLC6A4 (0.40) | MEN1KMT2AMPOCHRM5CHRM3 | |
| SCHEMBL21516391 | 0.81 | MPO (0.47) | MEN1KMT2AMPOCHRNA7CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |