SCHEMBL28526352

SCHEMBL28526352

Cc1cc(OC(=O)c2ccc(C(=O)O)cc2)cc(C(C)(C)C)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 5/20 0.54
RARG P13631 4/20 0.44
RARB P10826 3/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RARA P10276 3/20 0.42
ESRRA P11474 1/20 0.42
GLRA3 O75311 1/20 0.41
GLRB P48167 1/20 0.41
POLB P06746 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28526351 0.94 NR1H4 (0.59) NR1H4CYP1A2CYP2C9CYP2C19MAPT
SCHEMBL5081172 0.81 NR1H4 (0.51) NR1H4RARGRARBMAPTTDP1
SCHEMBL27974311 0.81 TDP1 (0.59) NR1H4MAPTTDP1L3MBTL1POLB
SCHEMBL28964346 0.81 NR1H4 (0.57) NR1H4MAPTTDP1L3MBTL1ESRRA
SCHEMBL38654691 0.80 MAPT (0.58) NR1H4MAPTTDP1L3MBTL1POLB
SCHEMBL5706719 0.77 CYP1A2 (0.52) NR1H4CYP1A2CYP2C9CYP2C19MAPT
SCHEMBL7705090 0.76 KMT2A (0.54) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL30924512 0.75 CYP1A2 (0.57) RARGRARBCYP1A2CYP2C9CYP2C19
SCHEMBL3807174 0.75 CYP1A2 (0.57) RARGRARBCYP1A2CYP2C9CYP2C19
SCHEMBL11351053 0.75 RXRA (0.48) NR1H4RARGRARBMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108495888-B Additive mixture for stabilizing polyols and polyurethanes 巴斯夫欧洲公司 2021-03-02 CN disclosed