SCHEMBL7705090

SCHEMBL7705090

Cc1cc(OC(=O)c2ccccc2)cc(C)c1O

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.54
MAPT P10636 5/20 0.54
MEN1 O00255 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
NSD2 O96028 1/20 0.54
ALDH1A1 P00352 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PKM P14618 1/20 0.51
TTR P02766 1/20 0.50
PARP10 Q53GL7 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
NPBWR1 P48145 1/20 0.50
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.46
F2 P00734 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7074980 0.89 KMT2A (0.47) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL7634289 0.88 KMT2A (0.46) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL11124466 0.86 NSD2 (0.69) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL11511170 0.86 KMT2A (0.54) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL28940650 0.84 KMT2A (0.54) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL11999789 0.84 KMT2A (0.53) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL27490485 0.83 TTR (0.52) KMT2AMAPTMEN1TTRGAA
SCHEMBL7711402 0.83 KMT2A (0.60) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL2755026 0.82 KMT2A (0.68) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL11072007 0.82 KMT2A (0.64) KMT2AMAPTMEN1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101044432-B Alkali development-type photosensitive resin composition, substrate with projections for liquid crystal division alignment control formed using the same, and liquid crystal display device TOPPAN PRINTING CO.,LTD. (JP) 2011-12-14 CN disclosed
CN-101044432-A Alkali development-type photosensitive resin composition, substrate with projections for liquid crystal division alignment control formed using the same, and liquid crystal display device TOPPAN PRINTING CO LTD (JP) 2007-09-26 CN disclosed
US-6358515-B2 ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION; TREATMENT OF GLAUCOMA SENJU PHARMACEUTICAL CO., LTD. (JP) 2002-03-19 US disclosed
US-20010008893-A1 HYDROQUINONE DERIVATIVES SENJU PHARMACEUTICAL CO., LTD. (JP) 2001-07-19 US disclosed
EP-0972766-A1 HYDROQUINONE DERIVATIVES Senju Pharmaceutical Co., Ltd. (JP) 2000-01-19 EP disclosed
US-5393776-A Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia BRISTOL-MYERS SQUIBB COMPANY (US) 1995-02-28 US disclosed
EP-0571928-A1 Acyclic Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia Bristol-Myers Squibb Company (US) 1993-12-01 EP disclosed
EP-0476493-A1 Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia Bristol-Myers Squibb Company (US) 1992-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010008893-A1 HYDROQUINONE DERIVATIVES REN, AGTR1, AGTR2 KMT2A 2128/4885MAPT 4729/4885MEN1 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.