SCHEMBL28526374

SCHEMBL28526374

Fc1c(P(F)(F)(F)F)ccc(C2CCCCC2)c1C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.37
FEN1 P39748 5/20 0.34
CEL P19835 2/20 0.33
ALOX5AP P20292 3/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27952428 0.72 CEL (0.44) ABCB1FEN1CELALOX5APPTGDR2
SCHEMBL239469 0.71 ABCB1 (0.43) ABCB1CELPTGDR2
SCHEMBL777739 0.69 PTPN5 (0.36) ABCB1FEN1CELALOX5APPTGDR2
SCHEMBL14353365 0.69 ABCB1 (0.42) ABCB1CELPTGDR2
SCHEMBL6882441 0.68 CEL (0.38) ABCB1CELPTGDR2
SCHEMBL777873 0.68 CEL (0.41) ABCB1CELPTGDR2
SCHEMBL260121 0.67 HTR1A (0.38) ABCB1CELPTGDR2
SCHEMBL301162 0.67 HTR1A (0.38) ABCB1CELPTGDR2
SCHEMBL301130 0.67 HTR1A (0.38) ABCB1CELPTGDR2
SCHEMBL28425765 0.67 ABCB1 (0.34) ABCB1FEN1CELPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166039-A Process for producing fluorovinylamide compound 大金工业株式会社 2021-07-23 CN disclosed
CN-112313200-A Process for producing fluorovinyl ether compound 大金工业株式会社 2021-02-02 CN disclosed