SCHEMBL28526463

SCHEMBL28526463

CC1(C)c2ccccc2-c2ccc(Br)cc2C1(C)C

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.54
PTPRC P08575 1/20 0.42
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
CYP2A6 P11509 1/20 0.35
S100A4 P26447 2/20 0.34
AKR1A1 P14550 1/20 0.34
AKR1B1 P15121 1/20 0.34
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TDP2 O95551 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17430723 0.89 PDK2 (0.44) PDK2PTPRCCYP2A6S100A4AKR1A1
SCHEMBL29387565 0.88 PDK2 (0.46) PDK2PTPRCTDP1L3MBTL1CYP2A6
SCHEMBL23923645 0.88 PDK2 (0.46) PDK2PTPRCTDP1L3MBTL1CYP2A6
SCHEMBL29469450 0.84 PDK2 (0.54) PDK2PTPRCOPRM1OPRD1TDP1
SCHEMBL24408 0.84 PDK2 (0.54) PDK2PTPRCOPRM1OPRD1TDP1
SCHEMBL29371626 0.84 PDK2 (0.54) PDK2PTPRCOPRM1OPRD1TDP1
SCHEMBL19757718 0.81 PDK2 (0.60) PDK2PTPRCOPRM1OPRD1TDP1
SCHEMBL16852578 0.81 PDK2 (0.60) PDK2PTPRCOPRM1OPRD1TDP1
SCHEMBL14174206 0.81 PDK2 (0.51) PDK2PTPRCOPRM1OPRD1TDP1
SCHEMBL15315869 0.80 ALDH1A1 (0.41) PDK2PTPRCKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022100704-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT APPARATUS AND DISPLAY DEVICE 阜阳欣奕华材料科技有限公司 2022-05-19 WO disclosed
CN-114478270-A Compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2022-05-13 CN disclosed
CN-112457201-A Compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2021-03-09 CN disclosed