Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 7/20 | 0.31 |
| ▸ | CA9 | Q16790 | 7/20 | 0.31 |
| ▸ | CA12 | O43570 | 6/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852647 | 1.00 | CA2 (0.35) | CA2CYP2D6THRBHSD17B10CA1 | |
| SCHEMBL8143628 | 0.86 | CA2 (0.41) | CA2CYP2D6THRBHSD17B10CA1 | |
| SCHEMBL11108863 | 0.86 | CYP2D6 (0.43) | CA2CYP2D6THRBHSD17B10CA1 | |
| SCHEMBL5756982 | 0.84 | CYP2D6 (0.42) | CA2CYP2D6THRBHSD17B10CA1 | |
| SCHEMBL13231375 | 0.79 | CYP2D6 (0.49) | CA2CYP2D6THRBHSD17B10CA1 | |
| SCHEMBL13410367 | 0.78 | CYP2D6 (0.54) | CA2CYP2D6THRBHSD17B10CA1 | |
| SCHEMBL11208480 | 0.77 | MEN1 (0.40) | CA2CA1CA9CA12MAPK1 | |
| SCHEMBL10604482 | 0.75 | — | — | |
| SCHEMBL5801560 | 0.73 | PTPN1 (0.38) | CA2CYP2D6CA1CA9CA12 | |
| SCHEMBL13262418 | 0.71 | CYP2D6 (0.44) | CA2CYP2D6THRBHSD17B10CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100166695-A1 | Multivalent Heterobifunctional Polymers And Methods Of Their Use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166695-A1 | Multivalent Heterobifunctional Polymers And Methods Of Their Use | PAICS, ILK, PARG | CA2 3406/4885CYP2D6 4579/4885THRB 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.