Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12272952 | 0.88 | KMT2A (0.42) | KMT2AMEN1ALDH1A1TP53PDK1 | |
| SCHEMBL1733957 | 0.81 | PDK1 (0.58) | KMT2AMEN1ALDH1A1TP53PDK1 | |
| SCHEMBL28530616 | 0.80 | AAK1 (0.45) | ALDH1A1ATM | |
| SCHEMBL8661235 | 0.80 | PDK1 (0.49) | KMT2AMEN1ALDH1A1TP53PDK1 | |
| SCHEMBL15618148 | 0.79 | MAPT (0.43) | KMT2AMEN1ALDH1A1PDK1PDK2 | |
| SCHEMBL15618164 | 0.78 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1PDK1PDK2 | |
| SCHEMBL645782 | 0.77 | PPARA (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL4704052 | 0.77 | PPARA (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL949969 | 0.77 | PPARA (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2312883 | 0.76 | KMT2A (0.46) | KMT2AMEN1ALDH1A1TP53PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |