Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 5/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 2/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095344 | 0.88 | SCN9A (0.46) | SCN9AKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL29669273 | 0.88 | SCN9A (0.46) | SCN9AKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL16109346 | 0.86 | SCN9A (0.48) | SCN9AKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL20449150 | 0.86 | SCN9A (0.46) | SCN9AKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL19631763 | 0.86 | SCN9A (0.46) | SCN9AKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL20449236 | 0.85 | SCN9A (0.46) | SCN9AKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL1109044 | 0.85 | SCN9A (0.47) | SCN9ASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL31093262 | 0.85 | SCN9A (0.43) | SCN9AKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL22088317 | 0.85 | SCN9A (0.43) | SCN9AKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL20449132 | 0.84 | SCN9A (0.45) | SCN9AKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109526219-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2021-03-12 | — | — | CN | disclosed |