Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830635 | 0.87 | GPR35 (0.50) | KDM4EMAPTGPR35ALDH1A1DAO | |
| SCHEMBL19433653 | 0.86 | PTPN2 (0.42) | KDM4EMAPTGPR35ALDH1A1CA12 | |
| SCHEMBL19433627 | 0.78 | CRBN (0.42) | KDM4EMAPTALDH1A1PTPN2ATM | |
| SCHEMBL28521802 | 0.78 | GPR35 (0.47) | KDM4EMAPTGPR35ALDH1A1DAO | |
| SCHEMBL31672932 | 0.77 | ATM (0.40) | KDM4EMAPTALDH1A1CA12CA1 | |
| SCHEMBL4827429 | 0.73 | PTPN2 (0.43) | KDM4EMAPTGPR35ALDH1A1PTPN2 | |
| SCHEMBL28529829 | 0.73 | RARB (0.46) | GPR35ALDH1A1DAOBCL2L1PTPN2 | |
| SCHEMBL11359596 | 0.73 | ALDH1A1 (0.54) | KDM4EMAPTGPR35ALDH1A1DAO | |
| SCHEMBL30643033 | 0.73 | GPR35 (0.76) | KDM4EMAPTGPR35ALDH1A1DAO | |
| SCHEMBL20916098 | 0.69 | CA12 (0.43) | KDM4EMAPTALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001345-B | Heterocyclic derivatives and use thereof | 株式会社C&C新药研究所 | 2021-03-02 | — | — | CN | disclosed |