Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2348802 | 0.89 | ALDH1A1 (0.46) | KCNH2SCN3AKDM4ETSHRSCN1A | |
| SCHEMBL15832346 | 0.89 | TSHR (0.46) | SMN1; SMN2KDM4ETSHRALDH1A1KMT2A | |
| SCHEMBL2346176 | 0.85 | MEN1 (0.47) | KCNH2SCN3ASMN1; SMN2POLBTSHR | |
| SCHEMBL28534238 | 0.83 | MEN1 (0.42) | KCNH2SMN1; SMN2KDM4EPOLBTSHR | |
| SCHEMBL21094085 | 0.83 | KCNH2 (0.44) | KCNH2SMN1; SMN2KDM4ETSHRALDH1A1 | |
| SCHEMBL4637526 | 0.82 | KCNH2 (0.56) | KCNH2SCN3ASCN1ASCN4ASCN7A | |
| SCHEMBL2350627 | 0.82 | KCNH2 (0.56) | KCNH2SCN3ASCN1ASCN4ASCN7A | |
| SCHEMBL3585032 | 0.82 | KCNH2 (0.56) | KCNH2SCN3ASCN1ASCN4ASCN7A | |
| SCHEMBL3585037 | 0.82 | KCNH2 (0.56) | KCNH2SCN3ASCN1ASCN4ASCN7A | |
| SCHEMBL4637528 | 0.82 | KCNH2 (0.56) | KCNH2SCN3ASCN1ASCN4ASCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |