Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21094112 | 0.87 | KCNH2 (0.46) | KCNH2KDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL29788146 | 0.86 | SLC6A3 (0.51) | KCNH2SLC6A3TP53MDM2 | |
| SCHEMBL2036846 | 0.86 | SLC6A3 (0.51) | KCNH2SLC6A3TP53MDM2 | |
| SCHEMBL2036845 | 0.86 | SLC6A3 (0.51) | KCNH2SLC6A3TP53MDM2 | |
| SCHEMBL24220439 | 0.85 | KCNH2 (0.49) | KCNH2ALDH1A1MAPTLMNA | |
| SCHEMBL20835748 | 0.85 | KCNH2 (0.49) | KCNH2ALDH1A1MAPTLMNA | |
| SCHEMBL2346176 | 0.84 | MEN1 (0.47) | KCNH2CACNA1DTP53ALDH1A1MEN1 | |
| SCHEMBL3600450 | 0.84 | ALDH1A1 (0.51) | KCNH2TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL28521573 | 0.84 | ALDH1A1 (0.51) | KCNH2TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL3600447 | 0.84 | ALDH1A1 (0.51) | KCNH2TP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |