Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673365 | 0.88 | NTMT1 (0.45) | NTMT1BCHEMAOBDPP4SMN1; SMN2 | |
| SCHEMBL28529152 | 0.85 | NTMT1 (0.44) | NTMT1BCHEMAOBDPP4SMN1; SMN2 | |
| SCHEMBL29033122 | 0.85 | CYP3A4 (0.50) | NTMT1BCHEMAOBDPP4SMN1; SMN2 | |
| SCHEMBL23632821 | 0.84 | NTMT1 (0.38) | NTMT1DPP4 | |
| SCHEMBL28976135 | 0.84 | NTMT1 (0.38) | NTMT1DPP4 | |
| SCHEMBL28062324 | 0.83 | CHRM3 (0.39) | DPP4SMN1; SMN2 | |
| SCHEMBL29276212 | 0.83 | BCHE (0.42) | NTMT1BCHEMAOBDPP4SMN1; SMN2 | |
| SCHEMBL29042797 | 0.82 | BCHE (0.41) | NTMT1BCHEMAOBDPP4SMN1; SMN2 | |
| SCHEMBL3247378 | 0.80 | SMN1; SMN2 (0.54) | NTMT1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL3243697 | 0.80 | SMN1; SMN2 (0.54) | NTMT1SMN1; SMN2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424207-B | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-112424207-A | NLRP3 inflammasome inhibitor | 诺华股份有限公司 | 2021-02-26 | — | — | CN | disclosed |