Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020022 | 0.73 | RXFP1 (0.43) | NPC1RAB9ARXFP1MAPK14ACKR3 | |
| SCHEMBL28532317 | 0.71 | RXFP1 (0.41) | NPC1RAB9ARXFP1MAPK14ACKR3 | |
| SCHEMBL15020021 | 0.67 | KDM4E (0.48) | NPC1RAB9ARXFP1KDM4E | |
| SCHEMBL15020163 | 0.67 | KDM4E (0.48) | NPC1RAB9ARXFP1KDM4E | |
| SCHEMBL22384253 | 0.64 | MAPT (0.41) | KDM4EMEN1MAPTKMT2AATM | |
| SCHEMBL12265872 | 0.63 | RAB9A (0.59) | NPC1RAB9ARXFP1MAPK14YEATS4 | |
| SCHEMBL2405269 | 0.62 | NPC1 (0.72) | NPC1RAB9ARXFP1PPARGNCOA2 | |
| SCHEMBL12529291 | 0.62 | L3MBTL1 (0.60) | NPC1RAB9ARXFP1SMN1; SMN2TSHR | |
| SCHEMBL12265900 | 0.62 | NPC1 (0.55) | NPC1RAB9ARXFP1YEATS4SMN1; SMN2 | |
| SCHEMBL27724862 | 0.62 | L3MBTL1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074820-B | GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112457301-A | Novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-03-09 | — | — | CN | disclosed |