Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537464 | 1.00 | TAAR1 (0.43) | TAAR1MEN1KMT2AHTR6KDM4E | |
| SCHEMBL28527431 | 1.00 | TAAR1 (0.43) | TAAR1MEN1KMT2AHTR6KDM4E | |
| SCHEMBL23487422 | 0.91 | KDM4E (0.49) | TAAR1MEN1KMT2AKDM4EATM | |
| SCHEMBL29589068 | 0.85 | CHRM5 (0.46) | TAAR1MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL29747061 | 0.85 | CHRM5 (0.46) | TAAR1MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL22165430 | 0.85 | CHRM5 (0.46) | TAAR1MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL23323069 | 0.85 | CHRM5 (0.46) | TAAR1MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL22165432 | 0.85 | CHRM5 (0.46) | TAAR1MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL28526280 | 0.84 | DRD2 (0.43) | TAAR1KDM4EATMCHRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL31198389 | 0.83 | CHRM5 (0.44) | TAAR1MEN1KMT2AKDM4ECHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |