Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471009 | 0.86 | MEN1 (0.46) | KDM4EPDE8BMEN1KMT2AHDAC1 | |
| SCHEMBL29091778 | 0.83 | GPR119 (0.46) | POLBKDM4EMEN1KMT2AGPR119 | |
| SCHEMBL28534357 | 0.82 | GPR119 (0.48) | POLBKDM4EGPR119UCHL1 | |
| SCHEMBL6150932 | 0.81 | LMNA (0.51) | MEN1KMT2ALMNANPSR1CCNA2 | |
| SCHEMBL28530608 | 0.80 | LMNA (0.40) | PDE8BMEN1KMT2AHDAC1GPR119 | |
| SCHEMBL1198309 | 0.80 | CCNA2 (0.55) | POLBHDAC1GPR119CCNA2CDK2 | |
| SCHEMBL30006703 | 0.80 | CCNA2 (0.55) | POLBHDAC1GPR119CCNA2CDK2 | |
| SCHEMBL31358156 | 0.79 | USP30 (0.49) | POLBGPR119CCNA2CDK2PIM1 | |
| SCHEMBL30721804 | 0.79 | CCNA2 (0.52) | POLBHDAC1GPR119CCNA2CDK2 | |
| SCHEMBL29151422 | 0.79 | CCNA2 (0.52) | POLBHDAC1GPR119CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |