Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718625 | 0.83 | MAPK1 (0.65) | HCAR3MAPK1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL30536224 | 0.81 | MAPK1 (0.54) | HCAR3MAPK1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL16445204 | 0.80 | HCAR3 (0.52) | HCAR3MAPK1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL16445205 | 0.80 | HCAR3 (0.52) | HCAR3MAPK1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28535213 | 0.80 | KDM4E (0.55) | MAPK1ALDH1A1GAAMAPT | |
| SCHEMBL8724028 | 0.79 | MAPK1 (0.61) | HCAR3MAPK1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL29065575 | 0.79 | MAPK1 (0.58) | HCAR3MAPK1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL22725450 | 0.79 | MAPK1 (0.58) | HCAR3MAPK1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL22725465 | 0.79 | MAPK1 (0.58) | HCAR3MAPK1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4129011 | 0.79 | HCAR3 (0.58) | HCAR3MAPK1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |