SCHEMBL285279

SCHEMBL285279

C=CCc1cc(C)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.58
RAB9A P51151 5/20 0.58
POLB P06746 2/20 0.52
LMNA P02545 2/20 0.51
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.40
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
PKM P14618 3/20 0.39
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
NPSR1 Q6W5P4 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384819 1.00 NPC1 (0.58) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL16046969 0.87 NPC1 (0.56) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL13550696 0.86 NPC1 (0.58) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL2724360 0.86 NPC1 (0.49) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL18593578 0.85 NPC1 (0.57) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL712510 0.85 NPC1 (0.43) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL31267541 0.84 NPC1 (0.66) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL29494818 0.84 NPC1 (0.66) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL258759 0.84 NPC1 (0.66) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL6381597 0.83 NPC1 (0.42) NPC1RAB9APOLBLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2115 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121541395-B Electrically tunable polymer stabilized cholesteric liquid crystal devices and methods of making the same 合肥工业大学 2026-05-22 CN claimed
CN-119463777-B Long-acting mildew-proof joint beautifying agent and preparation method thereof 广州白云科技股份有限公司 2026-05-19 CN claimed
WO-2026085960-A1 COMPOSITION HAVING MOSQUITO-REPELLING EFFECT AND PREPARATION METHOD THEREFOR 天津永阔科技发展有限公司 2026-04-30 WO claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
CN-120157993-A High-temperature-resistant PP bar and preparation method thereof 赣州恒信塑业有限公司 2025-06-17 CN claimed
CN-120137313-A Sheath material for saline-alkali drag-resistant cable, preparation method of sheath material and cable 特变电工新疆电缆有限公司 2025-06-13 CN claimed
CN-118931136-B Bio-based antibacterial packaging material and preparation method thereof 江苏省产品质量监督检验研究院 2025-06-13 CN claimed
CN-120082263-A Corrosion-resistant fluorocarbon baking varnish aluminum veneer and preparation method thereof 佛山市成特威金属科技有限公司 2025-06-03 CN claimed
CN-120059658-A Termite-proof silane modified MS sealant 安徽欣苗新材料科技有限公司 2025-05-30 CN claimed
US-6657029-B2 High refractive index monomer, greater amount of a hydrophilic monomer, crosslinker, and initiator; give water content; intraocular lenses BAUSCH & LOMB INCORPORATED 2003-12-02 US claimed
US-6657032-B2 High refractive index and hydrophilic monomers, a crosslinker, an initiator and water BAUSCH & LOMB INCORPORATED 2003-12-02 US claimed
US-20020049290-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-25 US claimed
US-20020042483-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-11 US claimed
US-20020042484-A1 High refractive index hydrogel compositions for ophthalmic implants BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-04-11 US claimed
US-20020037984-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-03-28 US claimed
US-6329485-B1 FOR INTRAOCULAR LENSES BAUSCH & LOMB INCORPORATED 2001-12-11 US claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO claimed
US-5910537-A GRAFT POLYMER OF HYDROPHOBIC AND HYDROPHILIC ACRYLIC AND/OR ALLELIC MONOMERS; NONHYDROLYZING; HIGH REFRACTIVE INDEX;DEFORMABLE CONTACT AND INTRAOCULAR LENSES STAAR SURGICAL COMPANY INC. (US) 1999-06-08 US claimed