SCHEMBL28528043

SCHEMBL28528043

C1CCCOCC1.N=C=O.N=C=O

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
TTR P02766 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29849299 1.00 ALDH1A1 (0.53) ALDH1A1TTRTSHR
Tetrahydrofuran SCHEMBL28200852 0.97
Tetrahydrofuran SCHEMBL20994813 0.97 ALDH1A1 (0.57) ALDH1A1TTRTSHR
Tetrahydrofuran SCHEMBL39001 0.97 ALDH1A1 (0.57) ALDH1A1TTRTSHR
Dioxane SCHEMBL28084964 0.82 TTR (0.50) ALDH1A1TTR
Dioxane SCHEMBL9469325 0.82
Tetrahydrofuran SCHEMBL1614767 0.82
Methane SCHEMBL28102196 0.79 TSHR (0.46) ALDH1A1TSHR
Oxirane SCHEMBL2594732 0.78
Oxirane SCHEMBL5690252 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108610481-B Polythiol composition having improved long-term storage stability and optical lens using the same SKC株式会社 2021-04-13 CN disclosed
CN-108610480-B Method for producing polythiol for optical lens using metal sulfide SKC株式会社 2021-03-12 CN disclosed