Tetrahydrofuran

Tetrahydrofuran

SCHEMBL39001

C1CCOC1.N=C=O.N=C=O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
TTR P02766 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28200852 1.00
Tetrahydrofuran SCHEMBL20994813 1.00 ALDH1A1 (0.57) ALDH1A1TTRTSHR
SCHEMBL28528043 0.97 ALDH1A1 (0.53) ALDH1A1TTRTSHR
SCHEMBL29849299 0.97 ALDH1A1 (0.53) ALDH1A1TTRTSHR
Dioxane SCHEMBL9469325 0.85
Dioxane SCHEMBL28084964 0.85 TTR (0.50) ALDH1A1TTR
Tetrahydrofuran SCHEMBL1614767 0.85
Methane SCHEMBL28102196 0.81 TSHR (0.46) ALDH1A1TSHR
Oxirane SCHEMBL5690252 0.81
Oxirane SCHEMBL2594732 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116790215-A Environment-friendly ceramic tile pure polyurea joint beautifying agent with strong durability and preparation method thereof 江苏缝小白新材料科技有限公司 2023-09-22 CN claimed
CN-111040620-A Radiation curable coating composition 英格维蒂英国有限公司 2020-04-21 CN claimed
CN-107001856-B Radiation curable coating composition 英格维蒂英国有限公司 2019-12-17 CN claimed
EP-3227396-B1 RADIATION CURING COATING COMPOSITION PERSTORP AB (SE) 2019-06-26 EP claimed
US-10167359-B2 Radiation curing coating composition PERSTORP AB (SE) 2019-01-01 US claimed
EP-2989138-B1 URETHANE ACRYLATES BASED ON 2,4,8,10-TETRAOXOSPIRO[5.5]UNDECANE-3,9-DIALKANOLS PERSTORP AB (SE) 2018-08-01 EP claimed
US-20170355807-A1 RADIATION CURING COATING COMPOSITION PERSTORP UK LTD (GB) 2017-12-14 US claimed
US-20170320887-A1 URETHANE ACRYLATES BASED ON 2,4,8,10-TETRAOXOSPIRO[5.5]-UNDECANE-3,9-DIALKANOLS PERSTORP AB (SE) 2017-11-09 US claimed
EP-3227396-A1 RADIATION CURING COATING COMPOSITION Perstorp AB (SE) 2017-10-11 EP claimed
WO-2017048169-A1 PROCESS FOR PRODUCING A WATER DISPERSIBLE, AIR DRYING COATING BINDER PERSTORP AB (SE) 2017-03-23 WO claimed
WO-2016089271-A1 RADIATION CURING COATING COMPOSITION PERSTORP AB (SE) 2016-06-09 WO claimed
EP-2989138-A1 URETHANE ACRYLATES BASED ON 2,4,8,10-TETRAOXOSPIRO[5.5]UNDECANE-3,9-DIALKANOLS PERSTORP AB (SE) 2016-03-02 EP claimed
WO-2014175802-A1 URETHANE ACRYLATES BASED ON 2,4,8,10-TETRAOXOSPIRO[5.5]UNDECANE-3,9-DIALKANOLS PERSTORP AB (SE) 2014-10-30 WO claimed
US-20110117282-A1 PROCESS OF OBTAINING A POLYURETHANE COATING COMPOSITION HAVING EXTENDED POT-LIFE RHODIE CHIMIE (FR) 2011-05-19 US claimed
US-3989768-A Chemically joined phase separated thermoplastic graft copolymers CPC INTERNATIONAL INC. (US) 1976-11-02 US claimed
CN-116790215-A Environment-friendly ceramic tile pure polyurea joint beautifying agent with strong durability and preparation method thereof 江苏缝小白新材料科技有限公司 2023-09-22 CN disclosed
EP-3470482-B1 COATING COMPOSITION JOTUN AS (NO) 2023-07-26 EP disclosed
US-3989768-A Chemically joined phase separated thermoplastic graft copolymers CPC INTERNATIONAL INC. (US) 1976-11-02 US disclosed
US-3987797-A ANTIMICROBIAL SUTURES ETHICON, INC. (US) 1976-10-26 US disclosed
US-3959191-A Novel hydrophobic polyurethane foams W. R. GRACE & CO. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170320887-A1 URETHANE ACRYLATES BASED ON 2,4,8,10-TETRAOXOSPIRO[5.5]-UNDECANE-3,9-DIALKANOLS ULK3, ULK2, DTYMK ALDH1A1 455/4885TTR 3008/4885TSHR 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.