Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032592 | 0.88 | CYP19A1 (0.60) | CYP19A1PRMT1POLBF2PRSS1 | |
| SCHEMBL2861011 | 0.84 | CYP19A1 (0.56) | CYP19A1PRMT1POLBF2PRSS1 | |
| SCHEMBL2852807 | 0.81 | BRAF (0.48) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6789998 | 0.81 | CA1 (0.57) | ALDH1A1TSHRTDP1CA2CA12 | |
| SCHEMBL6789995 | 0.81 | CA1 (0.57) | ALDH1A1TSHRTDP1CA2CA12 | |
| SCHEMBL174302 | 0.80 | GBA1 (0.57) | PKMALDH1A1CA2LMNACA1 | |
| SCHEMBL13508355 | 0.80 | GBA1 (0.57) | PKMALDH1A1CA2LMNACA1 | |
| SCHEMBL8762748 | 0.80 | CYP19A1 (0.62) | CYP19A1PRMT1POLBF2PRSS1 | |
| SCHEMBL922755 | 0.79 | CYP19A1 (0.66) | CYP19A1PRMT1POLBF2PRSS1 | |
| SCHEMBL1565027 | 0.79 | PRMT1 (0.73) | CYP19A1PRMT1POLBF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |