Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174302 | 1.00 | GBA1 (0.57) | GBA1PKMKMT2ATP53MAPT | |
| SCHEMBL6326386 | 0.90 | MMP1 (0.59) | ALDH1A1GRIA4 | |
| SCHEMBL15087835 | 0.90 | MMP1 (0.59) | ALDH1A1GRIA4 | |
| SCHEMBL27789020 | 0.87 | KMT2A (0.55) | GBA1PKMKMT2ATP53MAPT | |
| P-Toluenesulfonamide SCHEMBL16007442 | 0.85 | GBA1 (0.58) | GBA1PKMKMT2ATP53MAPT | |
| SCHEMBL674105 | 0.85 | ALDH1A1 (0.66) | GBA1PKMKMT2ATP53MAPT | |
| SCHEMBL4463262 | 0.84 | GBA1 (0.70) | GBA1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL3716602 | 0.84 | GBA1 (0.70) | GBA1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL3723855 | 0.84 | GBA1 (0.70) | GBA1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6324022 | 0.84 | CA1 (0.51) | GBA1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699189-B | Modulators of beta-3 adrenergic receptors useful for treating or preventing heart failure and disorders associated therewith | 艾尼纳制药公司 | 2025-02-18 | — | — | CN | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |