Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476670 | 0.79 | ITK (0.48) | MTNR1AMTNR1BITKHRH4FLT3 | |
| SCHEMBL21586308 | 0.78 | EHMT2 (0.50) | MTNR1AMTNR1BITKHRH4FLT3 | |
| SCHEMBL20033880 | 0.78 | ITK (0.47) | MTNR1AMTNR1BITKHRH4FLT3 | |
| SCHEMBL25787433 | 0.75 | ITK (0.45) | MTNR1AMTNR1BITKHRH4FLT3 | |
| SCHEMBL16562898 | 0.75 | ITK (0.48) | MTNR1AMTNR1BITKHRH4FLT3 | |
| SCHEMBL12755274 | 0.75 | ITK (0.45) | MTNR1AMTNR1BITKHRH4FLT3 | |
| SCHEMBL30963688 | 0.75 | DAO (0.53) | HRH4KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL21877855 | 0.74 | CA12 (0.53) | HRH4PSMB8KDM4EMEN1KMT2A | |
| SCHEMBL1550679 | 0.74 | ENPP2 (0.47) | MTNR1AMTNR1BITKHRH4FLT3 | |
| SCHEMBL20920169 | 0.74 | ALDH1A1 (0.49) | MTNR1AMTNR1BITKHRH4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112144074-B | Method for preparing dibit bromoindole by using electrochemical microchannel device | 南京先进生物材料与过程装备研究院有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-112144074-A | Method for preparing dibit bromoindole by using electrochemical microchannel device | 南京先进生物材料与过程装备研究院有限公司 | 2020-12-29 | — | — | CN | disclosed |