Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 6/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.33 |
| ▸ | CDK2 | P24941 | 6/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742150 | 0.83 | TNKS2 (0.50) | KDM4ESMN1; SMN2HTTCDC7CCNE1 | |
| SCHEMBL2457018 | 0.80 | KDM4C (0.52) | KDM4ESMN1; SMN2HTTKMT2ACDC7 | |
| SCHEMBL29540459 | 0.77 | NOS1 (0.36) | SMN1; SMN2HTTPTK2ALDH1A1 | |
| SCHEMBL3837505 | 0.73 | PNP (0.48) | KDM4ELMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL4141412 | 0.73 | CDC7 (0.47) | KDM4ERAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL15651633 | 0.68 | ROCK2 (0.46) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL1271080 | 0.67 | TNKS (0.58) | RAB9ASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL21072845 | 0.67 | KDM4E (0.54) | KDM4ERECQLLMNAKMT2ATNKS2 | |
| SCHEMBL17710780 | 0.67 | KDM4C (0.68) | KDM4ERECQLKDM4CALDH1A1MAPT | |
| SCHEMBL1685046 | 0.67 | TNKS2 (0.70) | KDM4ERECQLRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226807-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |