SCHEMBL28528447

SCHEMBL28528447

C=C(C)C(=O)OCCNC(=O)Nc1cccc(N)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDX3X O00571 2/20 0.52
ALDH1A1 P00352 2/20 0.50
EPHX2 P34913 4/20 0.47
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
EPHX1 P07099 3/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10093565 0.88 MAPT (0.63) ALDH1A1EPHX2MAPTGAANPSR1
SCHEMBL3252213 0.86 ALDH1A1 (0.49) ALDH1A1EPHX2MAPTGAANPSR1
SCHEMBL3252273 0.84 NPSR1 (0.55) ALDH1A1MAPTGAANPSR1EPHX1
SCHEMBL15356543 0.83 EPHX2 (0.46) EPHX2MAPTGAANPSR1EPHX1
SCHEMBL10093564 0.79 CNR1 (0.49) ALDH1A1EPHX2MAPTGAANPSR1
SCHEMBL12156588 0.79 ALDH1A1 (0.66) DDX3XALDH1A1MAPTEPHX1HDAC3
SCHEMBL1737201 0.79 EPHX2 (0.52) ALDH1A1EPHX2MAPTEPHX1KMT2A
SCHEMBL26662004 0.79 ALDH1A1 (0.50) ALDH1A1MAPTGAANPSR1EPHX1
SCHEMBL3246106 0.78 GAA (0.54) ALDH1A1MAPTGAANPSR1CA12
SCHEMBL1735929 0.78 CNR1 (0.44) ALDH1A1EPHX2MAPTGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108641043-B Self-repairing graft copolymer based on hydrogen bond effect and preparation method thereof 武汉纺织大学 2021-02-26 CN claimed
CN-108641043-B Self-repairing graft copolymer based on hydrogen bond effect and preparation method thereof 武汉纺织大学 2021-02-26 CN disclosed