SCHEMBL26662004

SCHEMBL26662004

C=C(C)C(=O)OCCOCCNC(=O)Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
LMNA P02545 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
GAA P10253 2/20 0.49
FPR2 P25090 1/20 0.49
EPHX1 P07099 4/20 0.49
KDM4E B2RXH2 1/20 0.49
HTT P42858 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.45
ACHE P22303 1/20 0.45
GPR174 Q9BXC1 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3252273 0.93 NPSR1 (0.55) ALDH1A1LMNAL3MBTL1RAB9ANPSR1
SCHEMBL26661999 0.88 ALDH1A1 (0.56) ALDH1A1LMNANPSR1GAAFPR2
SCHEMBL30099797 0.86 ALDH1A1 (0.65) ALDH1A1LMNAL3MBTL1RAB9ANPSR1
SCHEMBL26662008 0.86 EPHX1 (0.60) ALDH1A1LMNAEPHX1KDM4EHTT
SCHEMBL10093564 0.82 CNR1 (0.49) ALDH1A1LMNAL3MBTL1RAB9ANPSR1
SCHEMBL3253715 0.82 POLB (0.53) ALDH1A1RAB9ANPSR1GAAHTT
SCHEMBL16384916 0.81 THRB (0.61) ALDH1A1LMNAHTTSMN1; SMN2THRB
SCHEMBL13309606 0.81 THRB (0.61) ALDH1A1LMNAHTTSMN1; SMN2THRB
SCHEMBL3246106 0.81 GAA (0.54) ALDH1A1L3MBTL1RAB9ANPSR1GAA
SCHEMBL1735929 0.81 CNR1 (0.44) ALDH1A1LMNAL3MBTL1RAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12351542-B2 Spacered urea (meth)acrylates EVONIK OPERATIONS GMBH (DE) 2025-07-08 US disclosed
EP-4148040-B1 ONE POT SYNTHESIS OF UREA (METH)ACRYLATES EVONIK OPERATIONS GMBH (DE) 2023-11-01 EP disclosed
EP-4148041-B1 SPACERED UREA (METH)ACRYLATES EVONIK OPERATIONS GMBH (DE) 2023-11-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351542-B2 Spacered urea (meth)acrylates METTL14, METTL3, FUS ALDH1A1 382/4885LMNA 3075/4885L3MBTL1 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.