Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946719 | 0.84 | PLAAT3 (0.44) | HDAC2HDAC8CNR2PLAAT3PLAAT5 | |
| SCHEMBL27567318 | 0.84 | PLAAT3 (0.44) | HDAC2HDAC8CNR2PLAAT3PLAAT5 | |
| SCHEMBL31558750 | 0.84 | PLAAT3 (0.44) | HDAC2HDAC8CNR2PLAAT3PLAAT5 | |
| SCHEMBL694393 | 0.79 | ENPP2 (0.50) | HDAC2HDAC8PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL694394 | 0.79 | ENPP2 (0.50) | HDAC2HDAC8PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL23581826 | 0.78 | CYP3A4 (0.45) | HDAC2HDAC8CNR2ATMCYP3A4 | |
| SCHEMBL31558748 | 0.78 | HDAC2 (0.58) | HDAC2HDAC8CNR2CYP3A4BCL2L1 | |
| SCHEMBL26083980 | 0.78 | CYP19A1 (0.48) | HDAC2HDAC8TRIM24TRIM33CYP3A4 | |
| SCHEMBL18725055 | 0.78 | HDAC2 (0.40) | HDAC2HDAC8CNR2PLAAT3PLAAT5 | |
| SCHEMBL18725056 | 0.78 | HDAC2 (0.40) | HDAC2HDAC8CNR2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458904-B | N-substituted sulfonamide compound and process for producing the same | 宇部兴产株式会社 | 2021-12-03 | — | — | CN | disclosed |
| CN-106458903-B | Method for producing heteroaromatic sulfonamide compound | 宇部兴产株式会社 | 2021-02-05 | — | — | CN | disclosed |