SCHEMBL28528612

SCHEMBL28528612

CC(C)Cc1cccc(CC(C)C)c1CN

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.56
GABRB2 P47870 2/20 0.56
SLC6A2 P23975 2/20 0.37
TAAR1 Q96RJ0 2/20 0.37
PNMT P11086 2/20 0.37
MAOA P21397 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
CYP2A6 P11509 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
DPP4 P27487 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.33
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2743774 0.83 GABRA1 (0.62) GABRA1GABRB2SLC6A2TAAR1MAOA
SCHEMBL17329408 0.82 GABRA1 (0.43) GABRA1GABRB2DPP4
SCHEMBL13994811 0.79 GABRA1 (0.52) GABRA1GABRB2SLC6A2TAAR1PNMT
SCHEMBL19553768 0.78 PNMT (0.54) GABRA1GABRB2SLC6A2TAAR1PNMT
SCHEMBL2399172 0.78 GABRA1 (0.52) GABRA1GABRB2SLC6A2TAAR1MAOA
SCHEMBL677323 0.77 GABRA1 (0.56) GABRA1GABRB2SLC6A2TAAR1MAOA
Hydrochloric Acid SCHEMBL4599374 0.77 GABRA1 (0.50) GABRA1GABRB2SLC6A2TAAR1PNMT
SCHEMBL3960659 0.76 GABRA1 (0.60) GABRA1GABRB2SLC6A2TAAR1PNMT
Carbimide SCHEMBL28662233 0.76 GABRA1 (0.54) GABRA1GABRB2SLC6A2TAAR1MAOA
SCHEMBL9243360 0.76 GABRA1 (0.54) GABRA1GABRB2TAAR1ELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705848-B One-dimensional organic semiconductor nanocoil and preparation method and application thereof 中国科学院化学研究所 2021-02-26 CN disclosed