Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.38 |
| ▸ | ATP4B | P51164 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518880 | 0.80 | KMT2A (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL28529156 | 0.79 | ENPP2 (0.49) | ATP4AATP4BHSD17B10CYP2A6CTSA | |
| SCHEMBL7940868 | 0.78 | CYP2A6 (0.58) | CNR1CNR2ACHECYP2A6ALDH1A1 | |
| SCHEMBL13617123 | 0.75 | ALDH1A1 (0.45) | ATP4AATP4BCNR1CNR2HSD17B10 | |
| SCHEMBL28002826 | 0.75 | ALDH1A1 (0.42) | ATP4AATP4BCNR1CNR2ACHE | |
| SCHEMBL1339482 | 0.75 | AKR1C2 (0.50) | CNR1CNR2CTSAALDH1A1MEN1 | |
| SCHEMBL28358715 | 0.72 | CNR1 (0.40) | CNR1CNR2ACHECYP2A6CTSA | |
| SCHEMBL28354059 | 0.72 | CA1 (0.35) | CYP2A6KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL29956783 | 0.69 | CNR2 (0.44) | CNR1CNR2HSD17B10ACHEALDH1A1 | |
| SCHEMBL2932780 | 0.69 | CNR2 (0.44) | CNR1CNR2HSD17B10ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |