Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035255 | 0.85 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL10176597 | 0.83 | CYP4F2 (0.50) | KMT2ARXFP1MEN1ALDH1A1KDM4E | |
| SCHEMBL2848307 | 0.82 | MEN1 (0.63) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL2852904 | 0.81 | KMT2A (0.56) | KMT2ARXFP1MEN1ALDH1A1KDM4E | |
| SCHEMBL14025362 | 0.81 | MEN1 (0.62) | KMT2ARXFP1MEN1ALDH1A1KDM4E | |
| SCHEMBL20826191 | 0.80 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL2848539 | 0.79 | KDM4E (0.59) | KMT2AALDH1A1KDM4EGAALMNA | |
| SCHEMBL2224740 | 0.78 | KMT2A (0.52) | KMT2ARXFP1MEN1ALDH1A1KDM4E | |
| SCHEMBL2854838 | 0.78 | SMN1; SMN2 (0.63) | KMT2ARXFP1MEN1ALDH1A1GAA | |
| SCHEMBL15276891 | 0.76 | LMNA (0.70) | KMT2ARXFP1MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |