Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | WNT3 | P56703 | 2/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747729 | 0.84 | USP30 (0.44) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL20170496 | 0.84 | HSP90AA1 (0.56) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL23579324 | 0.83 | RIPK1 (0.47) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL22165572 | 0.83 | RIPK1 (0.47) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL29748129 | 0.83 | RIPK1 (0.47) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL6071600 | 0.82 | TSHR (0.55) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL19174905 | 0.82 | RIPK1 (0.46) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL3313724 | 0.82 | NR1H2 (0.57) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL31444419 | 0.82 | TSHR (0.55) | NPC1RIPK1TSHRMEN1KMT2A | |
| SCHEMBL3312132 | 0.82 | NR1H2 (0.57) | NPC1RIPK1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |