Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 17/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.72 |
| ▸ | CSF1R | P07333 | 2/20 | 0.72 |
| ▸ | FLT1 | P17948 | 2/20 | 0.72 |
| ▸ | KDR | P35968 | 2/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.72 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533721 | 0.92 | FLT3 (0.84) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL28523147 | 0.86 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL30237472 | 0.85 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL28907830 | 0.85 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL28524804 | 0.85 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL28540253 | 0.84 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL30237789 | 0.84 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL28527661 | 0.84 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL28529099 | 0.83 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR | |
| SCHEMBL28523144 | 0.83 | FLT3 (1.00) | FLT3PDGFRBCSF1RFLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321568-B | 4-methylpyrrole substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2023-02-17 | — | — | CN | claimed |
| CN-112321568-A | 4-methylpyrrole substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2021-02-05 | — | — | CN | claimed |
| CN-112321568-B | 4-methylpyrrole substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2023-02-17 | — | — | CN | disclosed |
| CN-112321568-A | 4-methylpyrrole substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2021-02-05 | — | — | CN | disclosed |