SCHEMBL28529361

SCHEMBL28529361

C=C(C(=O)OCCN(CC)CC)C(Cl)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.64
CYP1A2 P05177 4/20 0.64
CYP2D6 P10635 4/20 0.64
CYP3A4 P08684 5/20 0.63
ALDH1A1 P00352 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
KDM4E B2RXH2 3/20 0.53
CHRM2 P08172 6/20 0.53
CHRM1 P11229 6/20 0.53
CHRM3 P20309 5/20 0.53
TSHR P16473 2/20 0.53
HTR1A P08908 1/20 0.53
ADRA2A P08913 1/20 0.53
DRD1 P21728 1/20 0.53
SLC6A2 P23975 1/20 0.53
ADRA1A P35348 1/20 0.53
OPRM1 P35372 1/20 0.53
DRD3 P35462 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KCNH2 Q12809 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169629 0.86 CHRM1 (0.56) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
Ammonia Solution, Strong SCHEMBL28164353 0.85 CHRM1 (0.54) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
SCHEMBL10546414 0.82 CASP1 (0.55) LMNACYP1A2CYP2D6ALDH1A1SMN1; SMN2
SCHEMBL27075143 0.79 IDO1 (0.40) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
Adiphenine SCHEMBL27972992 0.79 LMNA (0.94) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
Adiphenine SCHEMBL248213 0.79 LMNA (1.00) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
SCHEMBL8070811 0.78 CHRM1 (0.45) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
Adiphenine SCHEMBL33478 0.77 CYP3A4 (1.00) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
SCHEMBL28779027 0.77 CYP2D6 (0.42) LMNACYP1A2CYP2D6CYP3A4ALDH1A1
SCHEMBL5930869 0.77 LMNA (0.58) LMNACYP1A2CYP2D6CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112538144-A Alkali-resistant sodium diisooctyl succinate sulfonate and preparation method thereof 广东灵捷制造化工有限公司 2021-03-23 CN claimed
CN-112538144-A Alkali-resistant sodium diisooctyl succinate sulfonate and preparation method thereof 广东灵捷制造化工有限公司 2021-03-23 CN disclosed