Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.43 |
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | MERTK | Q12866 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31054383 | 1.00 | MET (0.43) | METAXLMERTKKDRSCN9A | |
| SCHEMBL28529522 | 0.87 | MET (0.49) | METKDR | |
| SCHEMBL29773281 | 0.84 | MAPK14 (0.37) | METAXLMERTKKDR | |
| SCHEMBL28516905 | 0.83 | MET (0.39) | METAXLMERTKSCN9A | |
| SCHEMBL28523799 | 0.83 | MET (0.41) | METAXLMERTKKDRSCN9A | |
| SCHEMBL407596 | 0.78 | AXL (0.53) | METAXLMERTKKDR | |
| SCHEMBL28907382 | 0.75 | MET (0.44) | METAXLMERTKKDR | |
| SCHEMBL15578281 | 0.75 | L3MBTL1 (0.49) | METSCN9A | |
| SCHEMBL29773304 | 0.74 | TRPV1 (0.33) | MET | |
| SCHEMBL29248102 | 0.74 | AXL (0.37) | METAXLMERTKKDRSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793363-B | Substituted arylamino aromatic heterocyclic compound and application thereof as antitumor drug | 上海医药工业研究院 | 2021-02-26 | — | — | CN | disclosed |