Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 3/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538930 | 0.94 | MAPT (0.58) | MAPTMCL1NQO1ACP3AHR | |
| SCHEMBL28537348 | 0.87 | MAPK1 (0.44) | MAPTNQO1POLBGAAKMT2A | |
| SCHEMBL28537368 | 0.85 | KDM4E (0.45) | MAPTMCL1NQO1TP53GAA | |
| SCHEMBL28530799 | 0.83 | NQO1 (0.48) | NQO1ACP3KDM4EMAPK1 | |
| SCHEMBL28534246 | 0.82 | NQO1 (0.47) | MAPTNQO1KMT2AMEN1HTT | |
| SCHEMBL28539636 | 0.82 | TOP2A (0.39) | MAPTNQO1POLBKMT2AMEN1 | |
| SCHEMBL28534244 | 0.82 | TOP2A (0.39) | NQO1TP53POLBGAAKMT2A | |
| SCHEMBL28531636 | 0.78 | ACP3 (0.44) | NQO1ACP3KDM4EMAPK1ALDH1A1 | |
| SCHEMBL28531260 | 0.77 | KDM4E (0.42) | MAPTMCL1NQO1ACP3GAA | |
| SCHEMBL28908810 | 0.75 | VKORC1 (0.50) | MAPTNQO1TP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112517060-B | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112517060-A | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2021-03-19 | — | — | CN | disclosed |