Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537348 | 0.91 | MAPK1 (0.44) | KDM4EMAPK1GAAMGAMSI | |
| SCHEMBL28530799 | 0.87 | NQO1 (0.48) | KDM4EMAPK1NQO1TOP1 | |
| SCHEMBL28534246 | 0.85 | NQO1 (0.47) | KDM4EMAPK1MGAMNQO1MAPT | |
| SCHEMBL28534244 | 0.85 | TOP2A (0.39) | KDM4EMAPK1GAANQO1LMNA | |
| SCHEMBL28539636 | 0.85 | TOP2A (0.39) | KDM4EMAPK1NQO1MAPTLMNA | |
| SCHEMBL28529758 | 0.85 | MAPT (0.53) | KDM4EMAPK1GAANQO1MAPT | |
| SCHEMBL28531260 | 0.83 | KDM4E (0.42) | KDM4EMAPK1GAANQO1MAPT | |
| SCHEMBL28531636 | 0.82 | ACP3 (0.44) | KDM4EMAPK1NQO1ALDH1A1 | |
| SCHEMBL28910353 | 0.78 | NQO1 (0.44) | KDM4EMAPK1GAAMGAMNQO1 | |
| SCHEMBL28908810 | 0.78 | VKORC1 (0.50) | KDM4EMAPK1NQO1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112517060-B | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112517060-A | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2021-03-19 | — | — | CN | disclosed |